Abnormalities of free radical formation (FR) and antioxidant (AOX) reserve/capacity lead to conditions known as oxidative stress (OS) which plays a prominent role in the adaptive molecular response of cells, tissue and organs.

The pathogenesis of numerous clinical disorders has been documented, as well as identification of intra-intercellular sites using in vitro and in situ techniques.

Precise, direct or indirect analytical measurements can now be determined with state-of-the-art technology. ie; HPLC, ELISA, GS-MS, NMR, molecular biology and immunochemistry to evaluate FR, pro-oxidants, oxidized lipid, protein, DNA, aqueous/lipid soluble AOX components and AOX regulatory enzymes in a variety of biological fluids such as plasma, serum, erythrocytes, leukocytes, platelets, urine, saliva, tears, synovial fluid, semen and aspirates, as well as from biopsy specimens, tissue culture and plant sources.

                        Alteration of Metabolic Balance

Although the above mentioned approach has been routinely applied in basic research laboratories for sometime, medical and veterinary practitioners (conventional and alternative) are recognizing the potential of OS measurements in diagnosis/management. Many screening tests and biochemical profiles are available to assist in developing therapeutic strategies These are published in the 4 books displayed under publications.

A speakers bureau is available to conduct informational seminars on OS linked disease and known, or theoretical biochemical-pathophysiological mechanisms.

Please e-mail or call (386) 462-5371 during December through March, or (828) 689-8505 from April through November, for advice or assistance concerning problems you wish to address, or to pursue a course of action. Our combined consultation resources and analytical services supported by sophisticated computer programs which optimize biostatistical comparisons in OS, can be helpful and cost-effective to basic researchers, physicians, veterinarians, the health food industry, pharmaceutical companies and the lay public. We look forward to serving you.